AstraZeneca vaccine has major role to play, SA trial lead says

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Prof Shabir Madhi believes AstraZeneca's vaccine has a major role to play in Africa and globally, despite data showing it offers minimal protection against mild to moderate Covid-19.

SA has recorded the most coronavirus infections on the African continent and over 46,000 deaths. It aims to vaccinate 40 million people, or two-thirds of its population, to reach some level of herd immunity.

Madhi said it was likely the AstraZeneca shot would protect against severe Covid-19, since it was developed using a similar technology to the Johnson & Johnson vaccine, which has beenSA needed to recalibrate its expectations about vaccines this week after the trial showing reduced efficacy against mild-to-moderate illness caused by the more contagious 501Y.V2 variant, as well as to decide which groups to target and to start rolling out doses next week, he said.

“To start turning your back on a vaccine that could potentially save lives, I couldn't understand the logic behind it,” Madhi said. He said he would use the AstraZeneca vaccine to start protecting SA's elderly and those with comorbidities. The country's initial vaccination plan was to meant to start with health workers, but Madhi said the majority of the illness that was likely to occur among that group was mild to moderate infection and so the AstraZeneca jab would be better deployed on those at greater risk of severe illness.The world has experienced various coronavirus variants since the start of the pandemic and the first outbreak in China.

 

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