A scanning electron microscope image of SARS-CoV-2 emerging from the surface of cells cultured in the lab. WASHINGTON: An experimental COVID-19 vaccine that is being developed by US biotech firm Moderna induced antibody responses against the coronavirus in all 45 participants of a human trial, a paper published on Tuesday showed.
The 45 participants were split into three groups of 15 each to test doses of 25 micrograms, 100 micrograms and 250 micrograms.After the first round, antibody levels were found to be higher with higher level doses, and after the second round, participants had higher levels of antibodies than most patients who have COVID-19 and gone on to generate their own antibodies.
Andrew Freedman, an infectious disease expert at the University of Cardiff who was not involved in the study, said the paper suggested the vaccine"is able to stimulate antibody production in a dose-dependent fashion." "The side effects experienced by more than half the participants are quite common after other vaccinations, although the 'more severe adverse events' experienced by three of the subjects given the highest dose may mean that dose is too high to take forward," he said.
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