File photo of a macaque monkey. The researchers used Crispr to alter genes in pigs before transplanting their kidneys into macaques.File photo of a macaque monkey. The researchers used Crispr to alter genes in pigs before transplanting their kidneys into macaques.Researchers have claimed a major step forward in the field of organ transplantation after a monkey survived for more than two years with a genetically engineered pig kidney.
Scientists have spent decades working out whether animal organs could ever work properly and safely in humans without them being rejected by the patient’s immune system, but the challenges have proved immense.to alter genes in Yucatan miniature pigs before transplanting their kidneys into macaques. The modifications altered genes to prevent organ rejection and remove pig viruses that could potentially be activated in recipients.
“We are well on our way there,” Curtis said. “There simply aren’t enough kidneys to go around. In our opinion it’s the only near-term viable solution.”