Old Drug Verapamil May Have New Use in Type 1 Diabetes

In the AID part of the study, the 113 participants were randomized 2:1 to one of two commercially available AID systems plus frequent contact by study staff, or standard management using a continuous glucose monitor with an insulin pump or multiple daily injections.

Nonetheless, the change in C-peptide area under the curve did not differ between the two groups, decreasing from 0.57 pmol/mL at baseline to 0.45 pmol/mL at 52 weeks with the AID system, compared with a decrease from 0.60 pmol/L down to 0.50 pmol/L with standard care . Consequently, he said these findings are"a tough pill for us to swallow...but it's important for us in the field to understand."

"Excellent glycemic control has a benefit in and of itself, but it was not a successful intervention for beta-cell preservation."

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