Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Extended Data Fig. 1 Characterization of ZUMA-1 tumour biopsy specimens analysed in this study.
a, Heatmap of gene expression measured by PanCancer Immune Profiling panel in FFPE tumour biopsy specimens pretreatment or posttreatment from Zuma 1 patients with high or low tumour burden at pretreatment. Among the genes with significant differential expression between pre and post treatment , shown genes were selected according to their belonging to a specific TME related signature.
Extended Data Fig. 6 Correlative studies of Immunosign 21 score with cell subsets across 3 independent datasets.