Pfizer-BioNTech to seek US authorization for third COVID-19 shot in children

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Pfizer and BioNTech on Thursday announced positive results from a clinical trial on the safety and immune response of a third dose of their COVID-19 vaccine in children aged five through 11, adding they would soon seek US regulatory authorization.

Third doses of the vaccine are recommended for those aged 12 and up, and a fourth dose was recently recommended for people over 50.

In the phase 2/3 trial, the companies analyzed data from 140 children aged five through 11, approximately six months after the second dose. They also analyzed blood sera from a group of 30 individuals, finding that a third dose caused a 36-fold increase in levels of infection-blocking neutralizing antibodies against Omicron, compared to two doses.

 

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