g on volunteers in the United States, the companies plan to test the immune response generated by the Omicron-based vaccine both as a three-shot regimen in unvaccinated people and as a booster shot for people who already received two doses of their original vaccine.
"While current research and real-world data show that boosters continue to provide a high level of protection against severe disease and hospitalisation with Omicron, we recognise the need to be prepared in the event this protection wanes over time and to potentially help address Omicron and new variants in the future," Pfizer's head of vaccine research and development, Kathrin Jansen, said in a statement.
Some countries have already started offering additional booster doses, but a recent study from Israel showed that while a fourth dose of an mRNA vaccine boosted antibodies,BioNTech Chief Executive Ugur Sahin told Reuters in November that regulators would likely not require testing of an Omicron-based vaccine on humans because it and Pfizer had already created versions of their vaccine to target the earlier Alpha and Delta variants, with clinical trials continuing.
It said an analysis of antibodies elicited by its Omicron-targeted booster should help answer whether shots will be needed that address more than one variant at a time. It hopes to show the antibodies neutralise a spectrum of variants.
Omicron targeted vaccine by Pfizer ScottMorrisonMP GregHuntMP BradHazzard ChrisMinnsMP
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