COVID Vaccines for Kids Are Coming, but Not for Many Months

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As adults at high risk for COVID-19 line up to be immunized against the coronavirus, many parents want to know: When will my child get a vaccine? The short answer: Not before late summer. Pfizer and Moderna have enrolled children 12 and older in clinical trials of their vaccines and hope to have results by the summer. Depending on how the vaccines perform in that age group, the companies may then test them in younger children. The Food and Drug Administration usually takes a few weeks to review data from a clinical trial and authorize a vaccine. Sign up for The Morning newsletter from the New York Times Three other companies — Johnson & Johnson, Novavax and AstraZeneca — also plan to test their vaccines in children, but are further behind. When researchers test drugs or vaccines in adults first, they typically then move down the age brackets, watching for any changes in the effective dose and for unexpected side effects. “It would be pretty unusual to start going down into children at an early stage,” said Dr. Emily Erbelding, an infectious diseases physician at the National Institutes of Health who oversees testing of COVID-19 vaccines in special populations. Some vaccines — those that protect against pneumococcal or meningococcal bacteria or rotavirus, for example — were tested in children first because they prevent pediatric diseases. But it made sense for coronavirus vaccines to be first tested in and authorized for adults because the risk of severe illness and death from COVID-19 increases sharply with age, said Paul Offit, a professor at the University of Pennsylvania and a member of the FDA’s vaccine advisory panel. “We’re trying to save lives, keep people out of the ICU, keep them from dying,” Offit said. That means prioritizing vaccines for the oldest people and for those with underlying conditions. People younger than 21 account for about one-quarter of the population in the United States, but they make up less than 1% of deaths from COVID-19. Still, about

An undated photo provide by Cincinnati Children's Hospital shows Abhinav, 12, a participant in the Pfizer vaccine trial at Cincinnati Children's Hospital.

Some vaccines — those that protect against pneumococcal or meningococcal bacteria or rotavirus, for example — were tested in children first because they prevent pediatric diseases. But it made sense for coronavirus vaccines to be first tested in and authorized for adults because the risk of severe illness and death from COVID-19 increases sharply with age, said Paul Offit, a professor at the University of Pennsylvania and a member of the FDA’s vaccine advisory panel.

Scientists have estimated that 70% to 90% of the population might need to be immunized against the coronavirus to reach herd immunity, especially with more contagious variants expected to circulate widely in the country. Instead, the companies will look at vaccinated children for signs of a strong immune response that would protect them from the coronavirus.

Moderna’s vaccine, which was also authorized in December, is on a similar track for pediatric testing. In December, the company began testing adolescents ages 12 through 17, and plans to enroll 3,000 volunteers in this age group. The company expects results “around midyear 2021,” said Colleen Hussey, a spokeswoman for Moderna.

 

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